1. A vaccine that targets PCSK9 has been developed to treat high LDL-particle concentrations . 2. "We've seen almost 100 percent ozone depletion when we have high particle concentration ," 3. Drugs can inhibit PCSK9, leading to lowered circulating LDL particle concentrations . 4. At higher particle concentrations , the growing clusters may interlink, and form a particle gel. 5. Sparks attributed the poor sorting in ignimbrites to laminar flows of very high particle concentration . 6. For that reason, zero particle concentration does not exist. 7. Both FS 209E and ISO 14644-1 assume log-log relationships between particle size and particle concentration . 8. Dusty materials tend to generate aerosols with high particle concentrations measured in number or in mass. 9. Therefore, blocking PCSK9 can lower blood LDL-particle concentrations . 10. There are two other assays for LDL-particles, however, like LDL-C, most only estimate LDL particle concentrations .